专利名称：ANTI-VLA-4 RELATED ASSAYS
发明人：Tatiana Plavina,Paula S. Hochman,Michaela
Lerner
申请号：US16422822申请日：20190524
公开号：US20200088738A1公开日：20200319
摘要：Methods and apparatus for assaying the level of analytes in a sample, relatedto VLA-4, are disclosed. A method of decreasing the level of an anti-integrin antibody in asubject is described including a) contacting a biological sample from a subject with adetectable capture agent associated with a substrate, wherein the capture agent can bindan anti-integrin antibody in the sample; b) detecting binding of the capture agent with thelevel of the anti-integrin antibody; and c) treating the subject with plasma exchange untilthe level of the anti-integrin antibody in the sample reaches a predetermined level.
申请人：Biogen MA Inc.
地址：Cambridge MA US
国籍：US
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