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Tao protein kinases and methods of use therefor

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专利名称:Tao protein kinases and methods of use

therefor

发明人:MELANIE COBB,MICHELE HUTCHISON,ZHU

CHEN,KEVIN BERMAN

申请号:AU3560599申请日:19990414公开号:AU3560599A公开日:19991101

摘要:Compositions and methods are provided for potentiating the activity of themitogen-activated protein kinase p38. In particular the mitogen-activated protein kinasekinase MEK6, and variants thereof that stimulate phosphorylation of p38 are provided.Such compounds may be used, for example, for therapy of diseases associated with thep38 cascade and to identify antibodies and other agents that inhibit or activate signaltransduction via p38.

申请人:BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM

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