专利名称:Anti-VLA-4 related assays
发明人:Plavina, Tatiana,Hochman, Paula S.,Lerner,
Michaela
申请号:AU2010303156申请日:20101011公开号:AU2010303156B2公开日:20160204
摘要:Methods and apparatus for assaying the level of analytes in a sample, relatedto VLA-4, are disclosed. A method of decreasing the level of an anti-integrin antibody in asubject is described including a) contacting a biological sample from a subject with adetectable capture agent associated with a substrate, wherein the capture agent can bindan anti-integrin antibody in the sample; b) detecting binding of the capture agent with thelevel of the anti-integrin antibody; and c) treating the subject with plasma exchange untilthe level of the anti-integrin antibody in the sample reaches a predetermined level.
申请人:Biogen MA Inc.
代理人:Cullens Pty Ltd
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