专利名称：VITAMIN D ANALOGUES发明人：HESSE, Robert, Henry,RAMGOPAL,
Malathi,REDDY, Gaddam, Subba,SETTY,Sundara, Katugam, Srinivasasetty
申请号：EP94921070.2申请日：19940722公开号：EP0710227B1公开日：19981021
摘要：Novel 1α-hydroxy vitamin D derivatives in which the 17-position side chaincarries an azide or optionally substituted 1,2,3-triazole group, including compounds ofgeneral formula (I) where R1 represents a methyl group having α- or β- configuration; Wrepresents a valence bond or a C¿1-5? alkylene group; X represents azide or anoptionally substituted triazole group; and A= represents a cyclohexylidene moietycharacteristic of the A-ring of a 1α-hydroxylated vitamin D or analogue thereof. Activecompounds of the invention exhibit cell modulating activity while exhibiting a substantiallack of calcaemic effect.
申请人：RES INST MEDICINE CHEM
地址：US
国籍：US
代理机构：Marsden, John Christopher
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