Clavulanic acid derivatives, a process for their p

专利名称：Clavulanic acid derivatives, a process for

their preparation, their use, and

pharmaceutical compositions containingthem

发明人：Stirling, Irene,Clarke, Brian Peter申请号：EP79301284.0申请日：19790702公开号：EP0007717A1公开日：19800206

摘要：The present invention provides the compound of the formula (II): and estersthereof. These compounds are β-lactamase inhibitors and antibacterial agents.Pharmaceutical compositions containing them are described. A process for the

preparation of a compound of the formula (II) comprisesthe catalytic hydrogenation ofe.g. a compound of the formula (V): or a hydrogenolysable ester thereof, wherein R isisopropyl or isopropylene, and R and R together represents a butadiene moiety.

申请人：BEECHAM GROUP PLC

地址：Beecham House, Great West Road Brentford, Middlesex TW8 9BD GB

国籍：GB

代理机构：Hesketh, Alan (GB)

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