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Intrauterine fetal growth restriction

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专利名称:Intrauterine fetal growth restriction—the

treatment modalities for clinical research,and the biochemical rationale

发明人:Sumathi Paturu申请号:US10460170申请日:20030613公开号:US08252750B2公开日:20120828

摘要:Intrauterine Fetal Growth Restriction (IUGR) is a very important clinical problemfor which no satisfactory treatment is available so far. The current invention ofintravenous (IV) hypertonic glucose supplementation to the mother to improve theglucose transfer to the fetus at the intervillous space by improved facilitated diffusioncan be a safe and easy way of treating this problem, as the improved fetal blood glucosecan lead to fetal lipogenesis that can conserve the fetal O(oxygen) utilization and alsorelieve the associated metabolic derangements of fetal hypoxia, hypercapnia, andacidosis, apart from replenishing the oxidized coenzymes needed for the carbohydratemetabolism. The use of trans-amniotic fetal feeding studied by animal experiments canbe difficult in humans, because of the danger of infection, which can be overcome by theuse of implantable ports with a sterile patch technique.

申请人:Sumathi Paturu

地址:Pleasant Grove AL US

国籍:US

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