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Modulation of angiopoietin-like 3 expression

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专利名称:Modulation of angiopoietin-like 3 expression发明人:Freier, Susan M.,Graham, Mark J.,Crooke,

Rosanne M.

申请号:AU2014369900申请日:20141224

公开号:AU2014369900A1公开日:20160609

摘要:Provided herein are methods, compounds, and compositions for reducingexpression of an ANGPTL3 mRNA and protein in an animal. Also provided herein aremethods, compounds, and compositions for reducing lipids and/or glucose in an animal.Such methods, compounds, and compositions are useful to treat, prevent, delay, orameliorate any one or more of cardiovascular disease and/or metabolic disease, or asymptom thereof, in an individual in need thereof.

申请人:Ionis Pharmaceuticals, Inc.

代理人:Pizzeys Patent and Trade Mark Attorneys Pty Ltd

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